This aptamer exhibits specific binding and high affinity for the PTK7 receptor that is overexpressed in many cancer cells. We investigated a 41nt DNA aptamer as a theranostic agent for lymphoma and melanoma. Compared with antibodies, aptamers can beĮasily synthesized and chemically modified, rendering them a valuable tool for in vivo approaches. Nucleic acid aptamers can recognise their target with high affinity and specificity, and their potential as molecular imaging agents and use in theranostics are being explored. Preliminary in vivo characterization of a theranostic aptamer: Sgc8-c- DOTA-67GaĪptamer, Sgc8-c, PTK7, Molecular imaging, Theranostic
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